Clinical Trials/Research Opportunities

Neuromodulation-related Clinical Trial/ Research Study Opportunities

Below are neuromodulation-related research studies that are currently recruiting participants.

Depression

Repetitive Transcranial Magnetic Stimulation for Adolescent Depression

We are seeking adolescents (age 12-18 years) with depression that has not improved with at least 1 medication to participate in a research study at the University of Minnesota. The purpose of this study is to measure the feasibility, tolerability, and efficacy of a 6-week course of repetitive transcranial magnetic stimulation (rTMS).  Study activities include clinical interviews, a 6-week course of rTMS, and 2 brain MRI scans.  For more information and to find out if you or your child would qualify for our study, see our website at http://umnteenresearch.com/tms.htm or please call 612-626-7635.

Dystonia

Multimodal Assessment of Neurophysiology in Focal Dystonia

The Department of Rehabilitation Science at the University of Minnesota is currently conducting a research study titled:  Multimodal Assessment of Neurophysiology in Focal Dystonia.  The purpose of the study is to use magnetic resonance imaging (MRI) and transcranial magnetic stimulation (TMS) to determine the structure and excitability of the brain in healthy subjects and those diagnosed with laryngeal dystonia or spasmodic dysphonia to gain a better understanding of the causes of the disorder.

The study requires two ~2 hour visits at the University of Minnesota in Minneapolis.  Compensation is available for your participation for the amount of $200 ($75 for first visit, $125 for the second visit). Participation in this study is voluntary.  Your decision whether or not to participate in this study will not affect your current or future relations with the University, or your current health provider.  If you decide to participate, you are free to withdraw at any time without affecting those relationships.

To participate there are few requirements:

  • Between the ages of 21-75 years, however we are specifically in need of those 50-75
  • No history of seizure within the last two years

If you are interested in participating or have any questions regarding this study, please contact our lab by phone: (612) 626-0637 or by email:  tjklab@umn.edu

Cerebellar tDCS and Motor Learning

The Department of Rehabilitation Science at the University of Minnesota is currently conducting a research study titled: Cerebellar tDCS and Motor Learning.  This study will investigate the use of an experimental research device called transcranial direct current stimulation (tDCS).

If you have been diagnosed with cervical dystonia, you could be eligible to participate.  The study requires one ~2 hour appointment at the University of Minnesota in Minneapolis.  Compensation is given in a total of $30 Target gift cards to help compensate you for your time.  Participation in this study is voluntary.  Your decision whether or not to participate in this study will not affect your current or future relations with the University, the Fairview-University Medical Center.  If you decide to participate, you are free to withdraw at any time without affecting those relatinships.

If you are interested in participating or have any questions regarding this study, please contact: the Kimberly Lab by phone: (612) 626-0637 or by email: tjklab@umn.edu.  Or you may also contact the study principal investigator, Dr. Mo Chen at mchen@umn.edu.

Stroke

Infant Stroke:  Understanding Brain Reorganization

One in 2,300 babies have a stroke or bleeding in the brain.  These babies are at high risk of developing difficulty moving due to changes in the brain.  To provide treatment when it will potentially be most helpful, we first need to understand how the brain changes in babies after they have a stroke.

Using picutres and brain stimulation that does not require surgery, we will study these baby's brains and how they move. Looking at how the brain develops at this young age will help understand brain function in babies with stroke and create treatments with the goal to improve the baby's movement.

Please visit our website to learn more: z.umn.edu/infant

We invite you to contact us at 612-626-6415 or brown029@umn.edu for more information with no obligation to participate.

Title: Perinatal Stroke: Understanding Brain Reorganization through Infant Neuroimaging and Neuromodulation (ClinicalTrials.gov: NCT02743728)

Tinnitus

Tinnitus Research with Acoustic and Body Stimulation

The University of Minnesota’s Departments of Biomedical Engineering and Otolaryngology are seeking individuals who have tinnitus to participate in research involving acoustic stimulation, electrical stimulation of different skin surface regions, to potentially decrease the tinnitus percept. Participation involves up to 16 testing sessions that typically occur once every 2 weeks at the University of Minnesota.  Each testing session will require up to 3 hours.

Participants must be an adult between 18 and 65 years of age, have tinnitus preferably for less than 5 years, have no history of seizures, not be pregnant, and not have any implantable devices or indwelling metal.  Participants will receive compensation for their participation in each testing session in the form of Visa giftcards to cover their time and parking expense.  There is no charge for participating in this research.  For more information, please contact Yezihalem Mesfin, MS., at msync001@umn.edu.