Characterizing the pathophysiology across the pallido-cortical network and therapeutic pathway activation in dystonia using directional stimulation

In the United States approximately 300,000 people suffer from dystonia, making it the third most common movement disorder. Dr. Alberico's project aims to examine the intra-operative of neural activity in the motor and sensorimotor circuits as well as determining DBS pathway activation that will be used to determine optimal DBS parameters for treating patients with dystonia. This data will provide a better understanding of the pathophysiology of dystonia and the optimal location within the GPi for the treatment of dystonic symptoms, which may lead to reduced programming time, improved clinical outcomes, and provide a greater quality of life for dystonia patients.

Postdoctoral Fellow: Stephanie Alberico, Ph.D., Neurology

Mentor: Joshua Aman, Ph.D., Neurology