Optimizing closed-loop stimulation sequences to control beta band oscillations in Parkinson’s disease.

Dr. Farooqi's project aims to develop neural control systems with the precision and temporal specificity critical to characterizing the role of oscillatory dynamics in brain function. Using a closed-loop evoked-interference deep brain stimulation (iDBS) will optimally suppress or amplify oscillations in the subthalamic nucleus (STN) or globus pallidus (GPi) with varying amplitude and frequency in real-time. This is essential to advance the development of personalized DBS systems for Parkinson’s disease and other brain conditions.

In this project, Dr. Farooqi will develop a neuromodulation technique that has the potential to optimally modulate neural activity linked to Parkinson’s disease and thereby benefit the quality of life of Minnesota’s residents with this brain condition. The technologies developed in this project are an unmet need in the neuromodulation field and their commercialization could be an asset for the state’s economy.

Postdoctoral Fellow: Hafsa Farooqi, Ph.D.Biomedical Engineering

Mentor: Theoden Netoff, Ph.D., Biomedical Engineering