Real-time closed-loop TMS-EEG and tACS to investigate motor cortex excitability

Stroke, the biggest cause of movement deficiencies, by itself has a lifetime prevalence of 2.4% in Minnesota. It creates more than $400 million in hospitalization costs and impacts quality of life in thousands of individuals. Understanding motor cortical excitability is a crucial element to develop treatment in movement disorders, such as stroke, Parkinson’s disease, and many more. Dr. Wischnewski will investigate the causal relationship between neural oscillations and motor cortex activation, greatly advancing knowledge of neuromodulation and the human motor system. Proving superior effects of phase-specific stimulation of cortical oscillations on activation of the motor cortex will vastly improve treatment and training of motor skills. This study lays the groundwork for future clinical applications in rehabilitation of movement disorders.

Postdoctoral Fellow: Miles Wischnewski, Ph.D.Biomedical Engineering

Mentor: Alexander Opitz, Ph.D.Biomedical Engineering